WHO世界卫生组织：2025年关于怀孕、分娩和产间期镰状细胞疾病管理的建议报告（英文版）

Sickle-cell disease (SCD) is a group of autosomal recessive haemoglobin disorders that results from a gene mutation in the β-subunit of haemoglobin (1). It is a common inherited condition worldwide, affecting 7.74 million people (2). SCD is highly prevalent in sub-Saharan Africa, and causes a significant disease burden in other historically malaria-endemic regions of Africa, the Middle East, the Caribbean and South Asia. SCD also affects people in many other countries (2). Between 2000 and 20