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IVM:追踪基因相同且认知正常的老年双胞胎中临床前阿尔茨海默病的病程样本:双胞胎(英文版)

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2024-11-12
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IVM:追踪基因相同且认知正常的老年双胞胎中临床前阿尔茨海默病的病程样本:双胞胎(英文版).pdf
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Alzheimer’s disease (AD) is a neurodegenerative disease and the most common cause of dementia, contributing to 60-80% of cases above age 65.1 With approximately 55 million people living with dementia worldwide, which is predicted to increase to 150 million by 2050, it forms a large burden on society.2,3 Options for treatments are still limited, and one of the obstacles is that the precise pathophysiological processes that lead to dementia in AD remain largely unclear. Currently, the amyloid c


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