IQVIA艾昆纬：2025年肿瘤试验中联合治疗剂量优化白皮书：生物技术制药行业设计、建模及运营考量（英文版）

Combination therapies represent the future of oncology innovation, offering clinicians with regimens that have the potential to enhance efficacy, delay resistance and improve patients' responses and outcomes. Yet, determining dose optimization for such regimens is among the field's most complex challenges and requires rigorous operational and statistical planning and execution. This white paper reviews the design, operational, and analytic challenges that sponsors must consider when d