WHO世界卫生组织：2024年对pfhrp2基因删除的反应计划报告第二版（英文版）

The emergence of P. falciparum parasites with deletions in the pfhrp2 and pfhrp3 genes in most malaria-endemic regions poses a significant biological threat to malaria control. These parasites are undetectable by HRP2-based rapid diagnostic tests (RDTs) – the most commonly used test for malaria diagnosis – resulting in false-negative RDT results, which can have serious consequences for the management of malaria patients. Pfhrp2+/-pfhrp3 deletions have been reported in over 40 countries but h